ADVERTISEMENT

404

Not Found

Is this what you were looking for?

yr2001 mar profile 010305 html

Molecular Modeling in the Genomics Era
Christopher Smith | Mar 4, 2001 | 8 min read
Molecular Modeling, Visualization, and Structure Prediction Software (Additional material not included in the print edition) Courtesy of Theoretical Biophysics GroupBeckman InstituteUniversity of Illinois at Urbana-ChampaignThe photosynthetic reaction center of the purple bacterium, Rhodopseudomonas viridis (rendered using VMD) The aim of some life science researchers is to understand human physiology and the various diseases and mutations that can cause the body to go haywire. Accomplishing th
Death Watch I: Cytotoxicity Detection
Jorge Cortese | Mar 4, 2001 | 9 min read
Suppliers of Cytotoxicity Reagents (Part 1) Suppliers of Cytotoxicity Reagents (Part 2) Editor's note: This is the first in a two-part series on cell death. A second article on apoptosis will be published June 25. Courtesy of Loats AssociatesA comet assay showing degradation of 45 percent of the genomic DNA A few years ago the ultimate fate of dead cells was the laboratory trashcan. But cell necrobiology (the study of mechanisms of cell death) is now one of the hot fields of science.1 Cells c
Data-Sharing Forum Attracts a Crowd
Eugene Russo | Apr 1, 2002 | 4 min read
When Science published Celera Genomics Group's human genome paper last year, many scientists, especially bioinformaticians, were less than pleased with the unusual restrictions put on data access.1 The most odious: The data was not submitted to GenBank, and academic researchers were entitled to only one megabase of data at a time without further permission. Whitehead Institute for Biomedical Research's Center for Genome Research director Eric Lander, one of the most outspoken critics of the Scie
The Inequality of Drug Metabolism
Karen Young Kreeger | Mar 17, 2002 | 6 min read
Editor's Note: This is the fifth article in a series on sex-based differences in the biology of males and females. The final article in the series will cover sex-based differences in life expectancy. Lisa Damiani More than 30 years ago, researchers noted for the first time the pharmacokinetic differences between men and women. They found that women pass antipyrine, a drug used to study liver metabolism, more quickly than men; this occurred around ovulation and during the luteal phase of their m
The Rise of Biological Databases
Jennifer Fisher Wilson | Mar 17, 2002 | 6 min read
For this article, Jennifer Fisher Wilson interviewed Richard J. Roberts, chief U.S. editor of Nucleic Acids Research; Alex Bateman, group leader of Pfam at the Sanger Institute in Cambridge; and Peer Bork, head of the European Molecular Biology Laboratory's SMART team in Heidelberg, Germany, for SMART. Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. All four Hot Papers were published Jan
Is a Human Proteome Project Next?
Douglas Steinberg | Apr 1, 2001 | 10+ min read
Three dozen scientists, officials, and executives from academia, government, and business are speaking this week at a conference in McLean, Va., titled "Human Proteome Project: Genes Were Easy." This event, which is expected to draw at least 400 other participants, is the first sizable public meeting devoted to the possibility and advisability of a proteome project, according to organizer Chris Spivey, a conference director at Cambridge Healthtech Institute in Newton Upper Falls, Mass. The Vir
A Sharper Image
Bob Sinclair | Apr 29, 2001 | 10+ min read
Medical miracles abound, yet cancer continues to be a complex and challenging problem. "Cancer" is actually a generic, catchall term for the malignant tumors that are found in well over a hundred different diseases, but the basic concept is simple enough--a gene goes wrong and a tumor grows. Unfortunately, the reality is more complicated, involving an intricate sequence of phenomena and interactions in just a handful of the body's tens-of-trillions of cells. And therein lies the problem for rese

Run a Search

ADVERTISEMENT