NewsBlog: [Entry posted at 31st January 2006 06:22 AM GMT] Comment on this blog
NewsBlog: [Entry posted at 25th January 2006 05:35 PM GMT] A few days ago I blogged on a new fluorescent protein called KillerRed. Upon irradiation with green light KillerRed produces reactive oxygen species in sufficient quantities to kill both prokaryotic and eukaryotic cells.
The authors suggest several potential applications, but I?ve come up with another: hypoxia research. Before I joined The Scientist I was a postdoc in Celeste Simon's lab at the University of Pennsylvania. Simon works... Click to continue
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NewsBlog: [Entry posted at 23rd January 2006 10:42 PM GMT] A fundamental goal of systems biology is to define a biological system precisely, such that it becomes possible to predict the outcome of perturbing that system. Yesterday (Jan. 22) a team of researchers from German drug discovery firm Cellzome and the European Molecular Biology Laboratory reported in Nature a significant step toward the creation of such models, at least in budding yeast.
Giulio Superti-Furga... Click to continue
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NewsBlog: [Entry posted at 20th January 2006 10:50 PM GMT] Poking around on the iSpecies blog today, I found a comment alerting readers to an interesting little tool on the online version of Practical Fishkeeping, "the UK's best-selling aquarium magazine."
Fish Mapper is an applet that plots fish distribution data, culled from an online service called ... Click to continue
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NewsBlog: [Entry posted at 18th January 2006 02:40 PM GMT] Yesterday (Jan. 17) the Wellcome Trust Sanger Institute announced that its World Trace Archive database had just crossed the 1 billion sequence mark.
The Trace Archive is a collection of sequence reads, traces, and metrics from the world's sequencing facilities. It measures some 22 Terabytes in size and is doubling every 10 months, according to the press release. "To grasp how much data is in the... Click to continue
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NewsBlog: [Entry posted at 17th January 2006 10:09 PM GMT] This month?s Nature Biotechnology includes an article from Sergey Lukyanov that elevates fluorescent proteins from cool to killer.
Lukyanov, of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, and colleagues report the isolation of a GFP variant called KillerRed that acts as a photosensitizer. Photosensitizers produce reactive oxygen species upon stimulation with light;... Click to continue
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NewsBlog: [Entry posted at 10th January 2006 06:47 PM GMT] Researchers have, since 1988, been searching for a so-called "universal nucleant," that is, a material that will nucleate crystal formation, much as a grain of sand nucleates the formation of a pearl.
Buried in the biophysics section of PNAS's January 6 Early Edition is a somewhat esoteric paper that may just end this search -- and open one of structural biology's most persistent bottlenecks, generating high-quality... Click to continue
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Technically Speaking
Jeff Perkel
Location: Philadelphia, USA Who am I? Editor at The Scientist
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