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Identification of key cells in tumor growth
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2001, 2(1):20011101-02
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Bone marrow (BM)-derived precursor cells are thought to be involved in tumor angiogenesis but their precise role in tumor growth remains unknown. In November Nature Medicine, David Lyden and colleagues from Memorial Sloan-Kettering Cancer Center, New York report that tumor angiogenesis is dependent on recruitment of specific hematopoietic and circulating endothelial precursor cells (CEP). Blocking this process can efficiently inhibit tumor growth.
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