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Structure of a DNA damage repair protein
Email: David Bruce - david.bruce@biomedcentral.com News from The Scientist 2001, 2(1):20010809-02
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Damage to DNA strands resulting in breakage can lead to chromosomal translocation, uncontrolled cellular growth and cancer. These breaks can occur following exposure to agents such as ionizing radiation, or in programmed events such as gene shuffling. In mammalian cells this damage is repaired by a family of proteins involved in non-homologous end joining (NHEJ).
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