The Scientist : Aspirin targets myeloid dendritic cells [7/6/2001]

Email: Tudor Toma - ttoma@mail.dntis.ro
News from The Scientist 2001, 2(1):20010607-03

7 June 2001

Aspirin exerts a broad spectrum of pharmacological actions, including inhibition of activation of the transcription factor NF-κB and other molecular pathways of inflammation. In June 15 Journal of Immunology Holger Hackstein and colleagues from the Thomas E. Starzl Transplantation Institute at the University of Pittsburgh show that aspirin targets the dendritic cells responsible for triggering transplanted organ rejection.

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