The Scientist : strain differences influence host responses [19/3/2001]

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by Tudor Toma

RESEARCH ROUND-UP

H. pylori strain differences influence host responses

Differences in the ability of Helicobacter pylori strains to induce epithelial cell responses related to inflammation are dependent on the presence of an intact cag pathogenicity island.

Email: Tudor Toma - ttoma@mail.dntis.ro
News from The Scientist 2001, 2(1):20010319-01

Published

19 March 2001

Patients with chronic gastritis produced by Helicobacter pylori are at risk of duodenal and gastric ulceration and gastric cancer. The majority of H. pylori-colonized individuals remain asymptomatic, however, and the mechanism of this resistance is not fully understood. A study published in the March issue of Journal of Clinical Investigation shows that genetic differences between strains of Helicobacter pylori influence host inflammatory responses (J Clin Invest 2001, 107:611-620).

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