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by SPIS MedWire

RESEARCH ROUND-UP

Parkinson's disease not restricted to the brain
The hearts of many patients with Parkinson's disease have a reduced number of sympathetic nerve terminals.

Email: SPIS MedWire - medwire@sciencenow.com
News from The Scientist 2000, 1(1):20000905-02

Published 5 September 2000

LONDON, September 5 (SPIS MedWire). Parkinson's disease may not be restricted to the brain; it could also cause the loss of nerve terminals in the heart, according to new research. Scientists at the National Institute of Neurological Disorders and Stroke (NINDS), Maryland, USA, carried out positron emission tomography scans on 29 Parkinson's disease patients. Nearly all had reduced numbers of norepinephrine-producing nerve endings in the heart. This decrease was not related to whether the patients had taken the Parkinson's drug levodopa, or to the duration or severity of the disease. These findings could also explain some Parkinson's symptoms such as postural hypotension, dizziness and fainting.


 

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