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Single-Molecule Compaction of DNA
The Scientist 2004, 18(13):34
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Trying to segregate disorganized chromosomes is a feat akin to unpacking tangled Christmas lights. But through largely unknown processes, proteins called condensins help organize DNA during cell division. Using optical-trap microscopy, researchers recently analyzed an Escherichia coli condensin, MukBEF, which works like a "molecular Velcro," says Carlos Bustamante, a professor at the University of California, Berkeley.
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