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Learning A New HAT Trick
The Scientist 2004, 18(10):34
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Autoacetylation has neither the history nor the reputation of autophosphorylation, but the phenomenon may pull some weight. Researchers led by Philip Cole at The Johns Hopkins University School of Medicine confirmed that autoacetylation of the p300 histone acetyltransferase (HAT) leads to a greater than 10-fold acetylation activity enhancement.[1]
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