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RNAs Running the Show
Riboswitches raise some interesting questions about genetic regulation
The Scientist 2004, 18(10):26
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Coming from various directions, a number of research groups stumbled upon a naturally occurring mechanism for gene control that depends solely on RNA and environmental cues. Though the working details for this largely prokaryotic device are just now being revealed, so called riboswitches have thus far intrigued and impressed. "It's a completely new, unsuspected way of controlling gene expression," says David Lilley, professor of molecular biology, University of Dundee, Scotland
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