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Presynaptic Plasticity
The Scientist 2004, 18(9):35
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A group of slow-witted, mutant mice and a protein called RIM1α may provide insight into learning and memory mechanisms. University of Texas Southwestern researchers showed that knockout mice missing RIM1α, a presynaptic protein previously studied in vitro, performed worse at learning and memory tasks than did two other sets of genetically altered mice, each a mutant for proteins involved in neurotransmitter release.[1]
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