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TMA Buyers' Guide
Tissue microarrays come in various sizes and shapes; here's what you need to know before making your first purchase
The Scientist 2004, 18(5):44
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Barely five years ago, Juha Kononen, then at the National Cancer Institute, presented a straightforward way of constructing tissue microarrays (TMAs): a glass slide covered with as many as 1,000 cores of tissue, measuring from 0.6 mm to 2.0 mm in diameter.[1]
Suddenly, researchers could analyze gene expression and protein levels on hundreds of tissue samples by processing just one slide, instead of the hundreds previously required. As a result, scientists can better validate molecular markers of both development and disease.
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