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New Hydrogel Aids Protein Chip Development
Japanese team's new amphiphilic matrix facilitates protein characterization
The Scientist 2004, 18(4):39
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Put a piece of DNA on a clean, DNAase-free piece of glass, and it will probably still be there in its original state hours later. Proteins, though, are much less forgiving. They require specific coddling to maintain their correct three-dimensional conformation and enzymatic activity, a quality that has hampered the development of protein microarrays. To counter this problem, a group of researchers developed a new substance that might provide an optimal surface for preparing "semi-wet" protein chips.[1]
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